
Dr. Lydia Kitchen Dept. of Biosciences, Durham
Expansion microscopy is a transformative technology allowing super-resolution microscopy (SRM) through physical magnification on conventional microscopes. Furthermore, it acts as a clearing technique, allowing imaging deep into tissues, for example in plant science where tissue complexity limits other technologies. Durham Bioimaging Facility developed this technology for plants and the successful student will have a fantastic opportunity to extend this work, using a new method to significantly increase resolution further. The student will work with members of the bioimaging facility, to develop new plant-specific methods, building on our expertise and the growing field of expansion microscopy. They will produce the first images of plant cells/tissues at improved resolutions and gain skills in advanced optical microscopy, sample preparation, immunofluorescence staining and plant cell culture. Importantly, this placement will enable them to experience a technical career path and appreciate that research facilities are not only important for research support but are also centres of innovation. Students will need to find their own accommodation and be expected to present their findings orally at a research day in York in September 2025.