Mediators of megakaryocyte differentiation and platelet production in disease

FUNDING: 10 weeks (full time, 2 weeks in York, 8 weeks in US, £4,000 stipend, accommodation costs contribution, flight and VISA costs covered)
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LOCATION: Boston Children’s Hospital, Boston, USA
SUPERVISOR(S):

Dr. Kellie Machlus and Prof. Ian Hitchcock, Harvard Medical School, USA


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Each day the average human makes around 1011 blood platelets, which are crucial not just for clotting, but also in inflammation and disease. Our understanding of how platelets behave during these processes is important if we want to create new platelet-based therapies. Come join us in the Machlus Lab to work on one of our projects studying how blood platelets are made in the bone marrow by their precursor cells, megakaryocytes. We are located at Harvard Medical School in the heart of downtown Boston. We are in the Vascular Biology Program at Boston Children’s Hospital, where we have beautiful labs and state of the art core facilities. We are a very collaborative group and believe in both working and playing hard. We would love for you to join our team and see all the science that Harvard and Boston has to offer. Students will spend the first two weeks of the project with Kellie’s collaborators in York in the Hitchcock Lab and at the end be expected to present their findings orally at a research day in York in September 2023.