UV controlled dynamic covalent systems in supramolecular chemistry

FUNDING: 10 weeks (full time, 37 hrs per week, £12.60 per hour, £700 consumables, £500 student accommodation bursary)
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LOCATION: York, UK
SUPERVISOR(S):

Dr. Andrew West, Dept. of Chemistry, York


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Dynamic covalent systems are a topical research area in supramolecular chemistry, characterised by fast equilibration between multiple reaction components that can result in the preferential formation of selected complex products over many possible outcomes. This project will aim to explore a promising new dynamic reaction based on C=C/C=N bond metathesis. While this reaction has garnered significant interest, its equilibration at room temperature is relatively slow, taking approximately two hours. The project seeks to investigate methods to accelerate or control the reaction rate through UV irradiation. The student will focus on synthesising target molecules using well-established literature methods and laboratory techniques and then studying the dynamic covalent systems, employing NMR and UV/Vis spectrometry to monitor reaction progress. This project is well-suited for students with an interest in organic chemistry and reaction kinetics. Participants will have the opportunity to enhance their synthetic laboratory skills, gain hands-on experience with a variety of analytical techniques, and actively contribute to project planning and experimental design. Students will need to find their own accommodation and be expected to present their findings orally at a research day in York in September 2025.